Oxfordshire Clinical Commissioning Group
Formulary
 
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11 Eye
11-06 Prostaglandin analogues

Latanoprost 0.005% Eye drops
First Choice

Preserved latanoprost is available generically. Branded product £12.48 vs generic product £1.48. 

Prescribe generically. 

See Glaucoma and Ocular Hypertension Treatment Guidelines.

APCO March 2018.

Link  UKMI Q&A: Switching between travoprost and generic latanoprost eye drops
 

Amber Continuation  View adult BNF  View SPC online  View childrens BNF
Travoprost 0.004% Eye drops Travatan®
Second Choice

Suitable for prescribing in primary care following specialist recommendation.

See Glaucoma and Ocular Hypertension Treatment Guidelines.

APCO March 2018.

Link  UKMI Q&A: Switching between travoprost and generic latanoprost eye drops
 

Amber Continuation  View adult BNF  View SPC online  View childrens BNF
Bimatoprost 0.01% Eye drops Lumigan®
Third Choice

Third line choice in line with Glaucoma and Ocular Hypertension Treatment Guidelines.

NB. The 0.03% drops were discontinued at the end of April 2015.

APCO March 2018.


Amber Continuation  View adult BNF  View SPC online  View childrens BNF
Latanoprost 0.005% preservative free Monopost®
Restricted

For patients intolerant or who have allergies to the preservative containing preparations only in line with Glaucoma and Ocular Hypertension Treatment Guidelines.

Suitable for prescribing in primary care following specialist recommendation.

APCO March 2018.


Restricted Drug Amber Continuation  View adult BNF  View SPC online  View childrens BNF
Tafluprost (Preservative Free) 15micrograms/ml Saflutan®
Restricted

Second line if preservative-free treatment required in line with Glaucoma and Ocular Hypertension Treatment Guidelines.

NB. Latanoprost preservative free (Monopost®) is more cost-effective. 

APCO March 2018.


Restricted Drug Amber Continuation  View adult BNF  View SPC online  View childrens BNF
Bimatoprost 0.03% preservative free
Restricted

Third line if preservative-free treatment required in line with Glaucoma and Ocular Hypertension Treatment Guidelines.

APCO March 2018.


Restricted Drug Amber Continuation  View adult BNF  View SPC online  View childrens BNF
Bimatoprost with Timolol Ganfort®
Formulary

Suitable for prescribing in primary care following specialist recommendation, in line with Glaucoma and Ocular Hypertension Treatment Guidelines.

APCO March 2018.


Amber Continuation  View adult BNF  View SPC online  View childrens BNF
Latanoprost 0.005% with Timolol 0.5% PF Fixapost®
Formulary

For use if prostaglandin analogue + beta-blocker indicated and preservative free product required. To be included in updated glaucoma pathway.

APCO September 2019.


Amber Continuation  View adult BNF  View SPC online  View childrens BNF
Bimatoprost with Timolol Ganfort®
Restricted

For patients intolerant or who have allergies to the preservative containing preparations only in line with Glaucoma and Ocular Hypertension Treatment Guidelines.

Suitable for prescribing in primary care following specialist recommendation.

NB. Fixed combination product is cheaper for preservative free Ganfort(r) than individual component.

APCO March 2018.


Restricted Drug Amber Continuation  View adult BNF  View SPC online  View childrens BNF
Latanoprost 0.005% Eye drops Xalatan®
Non Formulary

Preserved latanoprost is generic and now less than half the price of all other prostaglandins. Prescribe generically.

MHRA/CHM advice (July 2015): Increased reporting of eye irritation since reformulation of Xalatan®

Following reformulation of Xalatan®, to allow for long-term storage at room temperature, there has been an increase in the number of reports of eye irritation from across the EU. Patients should be advised to tell their health professional promptly (within a week) if they experience eye irritation (e.g. excessive watering) severe enough to make them consider stopping treatment. Review treatment and prescribe a different formulation if necessary.

Link  Latanoprost (Xalatan): increased reporting of eye irritation since reformulation
 

View adult BNF  View SPC online  View childrens BNF
Latanoprost 0.005% with Timolol 0.5% Xalacom®
Non Formulary

Latanoprost 50micrograms/ml plus timolol 5mg/ml (generic) NOT RECOMMENDED. See Glaucoma and Ocular Hypertension Treatment Guidelines.

Switch patients to either latanoprost 50 micrograms/ml 1 drop affected eye at night PLUS timolol 0.25% 1 drop into the affected eye in the morning.

If compliance is an issue switch to travoprost 40 micrograms/ml plus timolol 5mg/ml fixed combination 1 drop affected eye daily. Switch can be done in primary care by GPs.

APCO March 2018.


Black View adult BNF  View SPC online  View childrens BNF