netFormulary Oxfordshire Clinical Commissioning Group NHS
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 Formulary Chapter 1: Gastro-intestinal system - Full Chapter
01.01  Dyspepsia and gastro-oesophageal reflux disease
01.01.01  Antacids and simeticone
01.01.01  Aluminium and magnesium containing antacids
Aluminium Only Preparations (Alu-Cap®)
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Restricted Drug Restricted
Brown

For renal patients only. 

 
   
Co-magaldrox (Maalox®)
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Restricted Drug Restricted
Brown

Available to purchase over the counter. 

Anyone requiring more than occassionally is likely to be more suitable for a PPI or equivalent, in line with Clinical Commissioning Policy 88D. 

 
   
01.01.01  Aluminium-magnesium complexes
01.01.01  Antacid preparations containing simeticone to top
Altacite plus®
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Restricted Drug Restricted
Brown

Restricted to Katharine House Hospice.

 
   
01.01.01  Simeticine alone
01.01.02  Compound alginates and proprietary indigestion preparations
01.01.02  Compound alginate preparations
Peptac®
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First Choice
Green
 
Gaviscon Infant®
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Formulary
Green

 

 
   
Gaviscon® Advance
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Restricted Drug Restricted
Brown

Available to purchase over the counter.

Anyone requiring more than occassionally is likely to be more suitable for a PPI or equivalent, in line with Clinical Commissioning Policy 88D

 
   
01.02  Antispasmodics and other drugs altering gut motility
01.02  Antimuscarinics to top
Hyoscine Butylbromide (Buscopan®)
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First Choice
Green
 
Glycopyrronium Bromide 320 mcg/ml (Sialanar®)
(Sialorrhoea)
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Formulary
Amber Continuation

Suitable for prescribing following initiation or recommendation from secondary care.

Licensed product (in children) for symptomatic treatment of severe sialorrhoea. Use in children and adults in line with NICE guidance (NG62, NG42 and NG31). 

NB. More cost-effective than unlicensed product. 

APCO May 2017. 

 
Link  NICE NG31: Care of dying adults in the last days of life
Link  NICE NG42: Motor neurone disease: assessment and management
Link  NICE NG62: Cerebral palsy in under 25s: assessment and management
   
Propantheline
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Formulary
Green
 
   
01.02  Other antispasmodics
Mebeverine
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First Choice
Green

135mg tablet only. 

 
Peppermint Oil (Colpermin®)
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Second Choice
Green

Available to purchase over the counter.

 
   
Alverine (Spasmonal®)
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Formulary
Green
 
   
01.03  Antisecretory drugs and mucosal protectants
01.03.01  H2-receptor antagonists
Ranitidine
(Tablets)
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Formulary

Green Traffic Light  For treatment of dyspepsia, gastro-oesophageal reflux disease and gastric/ duodenal ulceration. 

Brown Traffic Light For spontaneous urticaria (off-license) in line with Management Guideline for Spontaneous Urticaria with/without Angioedema in Adults

APCO November 2017.

 
   
Ranitidine
(Oral solution)
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Restricted Drug Restricted
Brown

The syrup is available for paediatric patients only. It is cheaper to disperse tablets for adults.

 
   
01.03.02  Selective antimuscarinics
01.03.03  Chelates and complexes to top
Bismuth subsalicylate (Pepto-Bismol®)
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Formulary
Green

Liquid and tablet preparations - available to purchase over the counter. 

For eradication of Helicobacter pylori, in line with Guidelines for Antibiotic Prescribing in the Community 2018.

APCO September 2018.

NB. Liquid is black-listed in drug tariff. 

 
   
Sucralfate
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Unlicensed Drug Unlicensed
Amber Continuation

Suitable for prescribing in primary care following specialist recommendation.

 
   
01.03.04  Prostaglandin analogues
Misoprostol (Cytotec®)
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Restricted Drug Restricted
Brown

Not first line for gastro protection. Consider PPI.

 
   
01.03.05  Proton pump inhibitors (PPIs)
Lansoprazole
(Capsules)
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First Choice
Green

Omeprazole capsules and lansoprazole capsules are the PPI preparations of choice.

For H.Pylori eradication see Guidelines for Antibiotic Prescribing in the Community 2018.

 
Omeprazole
(Capsules)
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First Choice
Green

Omeprazole capsules and lansoprazole capsules are the PPI preparations of choice.

For H.Pylori eradication see Guidelines for Antibiotic Prescribing in the Community 2018.

 
Omeprazole
(Dispersible tablets)
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Restricted Drug Restricted
Green

For patients with swallowing difficulties.

 
Link  Patient Information Leaflet: PPIs for the treatment of heartburn and indigestion.
   
Lansoprazole
(Orodispersible tablets)
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Restricted Drug Restricted
Green

For patients with swallowing difficulties.

 
Link  Patient Information Leaflet: PPIs for the treatment of heartburn and indigestion.
   
Esomeprazole
(40mg tablet)
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Restricted Drug Restricted
Green

Esomeprazole 40mg tablets only, can be used for patients with significant symptoms requiring very high dose PPI treatment.

APCO March 2011.

 
Link  Patient Information Leaflet: PPIs for the treatment of heartburn and indigestion.
   
Esomeprazole
(Granules)
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Restricted Drug Restricted
Green

For use in enteral tube patients where a small tube is being used or where blockage problems have occurred with lansoprazole orodispersible tablets/omeprazole dispersible tablets.

APCO July 2013.

 
Link  Patient Information Leaflet: PPIs for the treatment of heartburn and indigestion.
   
Omeprazole 10mg and 20mg Suspension
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Restricted Drug Restricted
Green

For use in enteral tube patients where a small tube is being used or where blockage problems have occurred with lansoprazole orodispersible tablets/omeprazole dispersible tablets/esomeprazole granules.

APCO May 2020.

 
   
01.03.06  Other ulcer-healing drugs
01.04  Acute diarrhoea
01.04.01  Adsorbents and bulk-forming drugs to top
01.04.02  Antimotility drugs
Loperamide
(Capsules)
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First Choice
Green

Available to purchase over the counter. 

 
Codeine
(Antidiarrhoeal)
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Second Choice
Green

Tablets 15mg, 30mg, Syrup (25mg/5mL).

 
   
Co-Phenotrope (Lomotil®)
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Third Choice
Green

Contains diphenoxylate (opioid) and atropine. Available for patients in whom loperamide and codeine have failed, but causes anticholinergic side effects.

Can be sold to the public for adults and children over 16 years (provided packs do not contain more than 20 tablets) as an adjunct to rehydration in acute diarrhoea (max. daily dose 10 tablets).

 
   
Eluxadoline (Truberzi®)
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Formulary
Amber Continuation

Suitable for continuation in primary care following specialist initiation for treating irritable bowel syndrome with diarrhoea as per NICE TA471. 

APCO November 2017.

 
Link  NICE TA471: Eluxadoline for treating irritable bowel syndrome with diarrhoea
Link  MHRA: Eluxadoline (Truberzi▼) - risk of pancreatitis
   
Loperamide
(Tablet & oral solution)
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Restricted Drug Restricted
Brown

Tablets are restricted for Gastroenterology and Colorectal patients requiring high doses who have swallowing difficulties (the tablets can be dispersed in water).

Oral solution (25mg/5ml) - unlicensedunlicensed - is available for short bowel syndrome where they need to give the smallest volume possible to aid absorption.

Oral solution (5mg/5ml) is available for any other patients with swallowing difficulties.

 
Link  MHRA: Serious cardiac adverse reactions with high doses of loperamide associated with abuse or misuse
   
01.04.03  Enkephalinase Inhibitors
01.05  Chronic bowel disorders
01.05.01  Aminosalicylates
Mesalazine (Octasa®)
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First Choice
Amber Continuation

Suitable for prescribing in primary care following specialist recommendation.

Prescribe by brand.

 
Mesalazine (Asacol®)
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Restricted Drug Restricted
Amber Continuation

For existing patients only - Octasa® brand is preferred for new patients as it is similar and more cost effective. 

 
   
Mesalazine (Pentasa®)
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Formulary
Amber Continuation

Suitable for prescribing in primary care following specialist recommendation.

Prescribe by brand.

 
   
Mesalazine (Salofalk®)
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Formulary
Amber Continuation

Suitable for prescribing in primary care following specialist recommendation.

Prescribe by brand.

 
   
Olsalazine
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Formulary
Amber Continuation

Suitable for prescribing in primary care following specialist recommendation.

 
   
Sulfasalazine
(Gastroenterology)
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Formulary
Amber Shared Care Protocol

For use in adult gastroenterology in line with Shared Care Protocol.

APCO March 2015.

 
   
01.05.02  Corticosteroids to top
Hydrocortisone (Colifoam®)
(Foam enema)
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First Choice
Green

First choice steroid foam enema for IBD.

 
Prednisolone
(Gastroenterology)
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Formulary
Green

Prescribe standard tablets only, enteric-coated tablets are black-listed due to lack of evidence of cost-efficacy.

APCO January 2011.

 
Link  UKMI Q&A: Prednisolone - Use plain, not EC tablets
Link  UKMI Q&A: Prednisolone - Use plain, not soluble tablets
   
Prednisolone (Predsol®)
(Rectal)
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Formulary
Green

Available as:

  • Retention enema and suppositories. 
  • Foam Enema - Hydrocortisone (Colifoam®) is first choice. Predfoam® has been discontinued, the generic replacement is more expensive than Colifoam®

 
   
Budesonide (Budenofalk®)
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Formulary
Amber Continuation

Suitable for prescribing in primary care following recommendation from gastroenterology only. 

Prescribe by brand name.

 
   
Budesonide (Cortiment MMX®)
(Ulcerative Colitis)
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Formulary
Amber Continuation

Alternative to prednisolone if not tolerated (at the second line stage of treatment for UC). OUH will provide initial 8 week course but further courses may be requested for GP to prescribe for repeat flare up or via IBD advice line.

Must be brand specific prescribing.

Clinic/ IBD advice line should send specific prescribing information to GPs if requested (email template to be developed).

APCO November 2018.

 
   
01.05.02  Oral
01.05.02  Topical
01.05.02  Parenteral
01.05.03  Drugs affecting the immune response
Cytotoxic Drug Azathioprine
(Gastroenterology)
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Formulary
Amber Shared Care Protocol

For inflammatory bowel disease in line with Shared Care Protocol.

APCO May 2011.

 
   
Ciclosporin
(Gastroenterology)
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Formulary
Amber Shared Care Protocol

*Ciclosporin must be prescribed by BRAND NAME.*

For induction and remission of ulcerative colitis (unlicensed) in line with Shared Care Protocol.

APCO May 2015.

 
Link  UKMI Q&A: Brand name prescribing in primary care
   
Cytotoxic Drug Mercaptopurine
(Gastroenterology)
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Formulary
Amber Shared Care Protocol

For the treatment of inflammatory bowel disease in line with Shared Care Protocol.

APCO November 2015.

 
   
Cytotoxic Drug Methotrexate 2.5mg tablets
(Gastroenterology)
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Formulary
Amber Shared Care Protocol

Only 2.5mg tablets should be prescribed and dispensed to avoid potentially fatal errors.

For use in adults and paediatrics line with Shared Care Protocol for:

  • Dermatology
  • Neurology
  • Gastroenterology
  • Respiratory

Rheumatology

For rheumatology please prescribe in line with Shared Care Protocol here. 

APCO September 2019

Opthalmology

For opthalmology (ocular inflammation) please prescribe in line with Shared Care Protocol here. 

APCO May 2019.

 
   
Cytotoxic Drug Methotrexate injection (Metoject®)
(Gastroenterology)
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Formulary
Amber Shared Care Protocol

*Metoject® injection is the first choice brand of injection which should be used in Oxfordshire*

For use in adults and paediatrics line with Shared Care Protocol for:

  • Dermatology
  • Neurology
  • Gastroenterology
  • Respiratory

Rheumatology

For rheumatology please prescribe in line with Shared Care Protocol here. 

APCO September 2019

Opthalmology

For opthalmology (ocular inflammation) please prescribe in line with Shared Care Protocol here. 

APCO May 2019.

 
   
Vedolizumab (Entyvio®)
(Gastroenterology)
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Formulary
Red
High Cost Medicine
BlueTeq

For the treatment of:

    • Moderately to severely active ulcerative colitis as per NICE TA342 (APCO July 2015). Also see Clinical Commissioning Policy 263 (ulcerative colitis in adults).
    • Moderately to severely active Crohn's disease after prior therapy as per NICE TA352 (APCO January 2017).

 

 
Link  NICE TA352: Vedolizumab for treating moderately to severely active Crohn’s disease after prior therapy
Link  NICE TA342: Vedolizumab for treating moderately to severely active ulcerative colitis
   
01.05.03  Cytokine inhibitors to top
Adalimumab (Humira®)
(Gastroenterology)
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Formulary
Red
High Cost Medicine
BlueTeq

For the treatment of:

 

 
Link  NICE TA187: Crohn’s disease - infliximab and adalimumab
Link  NICE TA329: Infliximab, adalimumab and golimumab for moderately to severely active ulcerative colitis
   
Golimumab (Simponi®)
(Gastroenterology)
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Formulary
Red
High Cost Medicine
BlueTeq

For treating moderately to severely active ulcerative colitis after the failure of conventional therapy as per NICE TA329. Also see Clinical Commissioning Policy 263 (ulcerative colitis in adults).

APCO March 2013.

 
Link  NICE TA329: Infliximab, adalimumab and golimumab for moderately to severely active ulcerative colitis
   
Infliximab
(Gastroenterology)
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Formulary
Red
High Cost Medicine
BlueTeq

For the treatment of:

 
Link  NICE TA163: Ulcerative colitis (acute manifestations) Infliximab
Link  NICE TA187: Crohns disease - infliximab & adalimumab
Link  NICE TA329: Infliximab, adalimumab and golimumab for moderately to severely active ulcerative colitis
Link  SPS: Biosimilars of infliximab guidance
   
Ustekinumab (Stelara®)
(Gastroenterology)
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Formulary
Red
High Cost Medicine
BlueTeq

For treating moderately to severely active Crohn’s disease after previous treatment as per NICE TA456.

APCO September 2017.

 
Link  NICE TA456: Ustekinumab for moderately to severely active Crohn’s disease
   
01.05.04  Food allergy
01.06  Laxatives
01.06.01  Bulk-forming laxatives
Ispaghula Husk (Fybogel®, Ispagel® Orange)
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Formulary
Green

Available to purchase over the counter. 

 
   
01.06.02  Stimulant laxatives
Bisacodyl (Dulcolax®)
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Formulary
Green

Available to purchase over the counter.

 
   
Co-danthrusate
(Dantron)
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Formulary
Green

For constipation in terminally ill patients.

 
   
Docusate Sodium (Diotyl®, Docusol®)
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Formulary
Green

  • Diotyl® capsule
  • Docusol® solution (Utterly unpalatable - only fit for use down tubes.

 
   
Glycerol (Glycerin)
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Formulary
Green

Moisten suppository with water before use. Available to purchase over the counter. 

 
   
Senna
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Formulary
Green

Available as tablet and syrup (strong taste may be disliked by some).

Available to purchase over the counter. 

 
   
Sodium hydrogen carbonate / sodium dihydrogen phosphate (Lecicarbon A®)
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Formulary
Amber Continuation

For use if other laxatives have failed, specifically on recommendation from the pelvic floor clinic.

APCO July 2019.

 
   
Sodium Picosulfate (Dulco-lax®)
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Formulary
Green

Elixir or sachets available. Available to purchase over the counter. 

 
Link  Medicines for Children leaflet: Sodium picosulfate for constipation
   
01.06.03  Faecal softeners to top
Arachis Oil
(Fletchers arachis oil retention enema)
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Formulary
Green

Do not give to patients with PEANUT ALLERGY.

Warm before use. 

 
Link  UKMI Q&A: Arachis oil in medicines – what are the risks of developing peanut allergy?
   
01.06.04  Osmotic laxatives
Macrogol oral powder (Laxido®)
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First Choice
Green

For the management of acute general constipation in adults.

 
Lactulose
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Formulary
Green
 
   
Macrogol oral powder (Movicol® Paediatric)
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Restricted Drug Restricted
Brown

For paediatric use only.

 
   
Magnesium Hydroxide Mixture BP
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Formulary
Green

Aqueous suspension containing about 8% hydrated magnesium oxide. Do not store in cold place.

 
   
Micro-enema
(Micolette®, Micralax®)
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Formulary
Green
 
   
Phosphates (Rectal)
(Fleet® ready to use enema)
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Formulary
Green

Enema

 
   
01.06.05  Bowel cleansing preparations
Bowel Cleansing Solutions (Citramag®)
(Magnesium Citrate)
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Formulary
Red

Secondary care use only.

 
   
Fleet Phospho-soda®
(Oral solution)
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Formulary
Red

Oral solution. Secondary use only for bowel evacuation before colonic surgery, colonoscopy or radiological examination.

 
   
Macrogols (Klean-Prep®)
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Formulary
Red

Secondary care use only.

 
   
Macrogols (Moviprep®)
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Formulary
Red

Secondary care use only for bowel preparation for colonoscopies. Patients with stage 4 and 5 CKD (i.e.: GFR < 30ml/min) and patients unable to tolerate standard therapy (citramag® and senna) only.

 
   
Picolax®
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Formulary
Red

Secondary care use only. 

 
   
01.06.06  Peripheral opioid-receptor antagonist
Naloxegol
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Restricted Drug Restricted
Brown

For the treatment of opioid-induced constipation as per NICE TA345. To be recommended by palliative care and gastroenterology only.

APCO September 2015.

 
Link  NICE TA345:Naloxegol for treating opioid‑induced constipation
   
01.06.07  Other drugs used in constipation
Prucalopride (Resolor®)
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Restricted Drug Restricted
Brown

For restricted use in line with NICE TA211 for people with chronic idiopathic constipation:

  • Who have previously been treated with 2 different types of laxatives at the highest possible recommended dose, for at least 6 months, but these haven't worked well enough, and
  • When invasive treatment is being considered.


APCO May 2012.

 
Link  NICE TA211: Constipation (women) - prucalopride
   
01.07  Local preparations for anal and rectal disorders to top
01.07.01  Soothing haemorrhoidal preparations
01.07.02  Compound haemorrhoidal preparations with corticosteroids
Anusol-HC
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Restricted Drug Restricted
Brown

Available to purchase over the counter, in line with Clinical Commissioning Policy 88D.

 
   
Proctofoam HC
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Formulary
Red

Secondary care use only for radiotherapy usage.

 
   
Scheriproct® suppositories
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Restricted Drug Restricted
Brown

Contains cinchocaine and prednisolone. 

Prescribe when OTC preparations containing steroid and local anaesthetic are ineffective, in line withClinical Commissioning Policy 88D.

 
   
Xyloproct® ointment
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Restricted Drug Restricted
Brown

Ointment containing lidocaine and hydrocortisone. 

Prescribe when OTC preparations containing steroid and local anaesthetic are ineffective, in line with Clinical Commissioning Policy 88D.

 

 
   
01.07.03  Rectal sclerosants
Oily phenol injection BP
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Formulary
Red
 
   
01.07.04  Management of anal fissures
Glyceryl trinitrate 0.4% rectal ointment (Rectogesic®)
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Restricted Drug Restricted
Brown

Restricted use for anal fissure after lifestyle advice or use of topical anaesthetic prior to specialist referral. Licensed and easily available.

APCO June 2007.

 
Link  UKMI Q&A: Is topical glyceryl trinitrate for anal fissure compatible with breastfeeding?
   
Diltiazem 2%  (Anoheal®)
(cream)
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Unlicensed Drug Unlicensed
Red

For chronic anal fissure, second line to GTN for use by secondary care only.

APCO January 2019.

 
   
01.08  Stoma care to top
Stoma Care
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Formulary
Green

For expert advice on stoma care contact clinical nurse specialist in stoma therapy.

Patients and their carers are usually given advice about the use of cleansing agents, protective creams, lotions, deodorants, or sealants whilst in hospital, either by the surgeon or by stoma care nurses. Voluntary organisations offer help and support to patients with stoma.

 
Link  Good Practice Guidance: Stoma Appliances in Care Homes
Link  OCCG Guidance on Stoma Prescribing
   
01.09  Drugs affecting intestinal secretions
01.09.01  Drugs affecting biliary composition and flow
Ursodeoxycholic acid (Ursofalk®)
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Formulary
Amber Continuation

Suitable for prescribing in primary care following specialist recommendation.

 
   
Obeticholic acid (Ocaliva®)
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Formulary
Red

For treating primary biliary cholangitis as per NICE TA433.

Funded by specialised commisiong. 

APCO July 2017.

 
Link  NICE TA443: Obeticholic acid for treating primary biliary cholangitis
   
01.09.02  Bile acid sequestrants
Colestyramine
(Gastroenterology)
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Formulary
Green

Powder, sugared and sugar free options

 
   
01.09.03  Aprotinin
01.09.04  Pancreatin to top
Pancreatin (Creon®)
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First Choice
Amber Continuation

Suitable for prescribing in primary care following specialist recommendation.

Capsule: Available as Creon® 10000, 25000, 40000
Restricted Item Granules: Creon Micro® should only be used for paediatrics as the dose is easier to measure.

 
Pancreatin (Nutrizym® 22)
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Second Choice
Amber Continuation

Suitable for prescribing in primary care following specialist recommendation. 

Second line option for those intolerant of Creon.

Pancrease HL® and Nutrizym 22® should not be used in children aged 15 years or less with cystic fibrosis due to risk of the development of large bowel strictures (fibrosing colonopathy).

 
   
Pancreatin (Pancrex® V)
(Powder)
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Second Choice
Amber Continuation

Suitable for prescribing in primary care following specialist recommendation. 

Powder and capsules only.  Tablets are non-formulary. 

2g Pancrex V powder is approximately to one level 2.5ml spoonful.

 
   
 ....
 Non Formulary Items
Acidex

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Non Formulary
 
Algicon®

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Non Formulary
 
Anugesic-HC®

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Non Formulary

Suppositories discontinued September 2013. 

 
Asilone

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Non Formulary

Product discontinued. 

 
Atropine
(Tablets)

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Non Formulary
 
Balsalazide Sodium  (Colazide®)

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Non Formulary
Black

For ulcerative colitis. 

APCO June 2007.

 
Beclometasone  (Clipper®)

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Non Formulary
 
BLI-800  (Eziclen®)

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Non Formulary
 
Botulinum toxin type A

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Non Formulary
Black

Not normally funded for chronic anal fissure due to lack of high quality evidence of clinical and cost effectiveness. In line with Clinical Commissioning Policy 254A.

 
Budesonide  (Entocort®)

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Non Formulary
 
Cholic acid  (Kolbam®)

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Non Formulary
 
Cholic acid  (Orphacol®)

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Non Formulary
 
Cimetidine

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Non Formulary
 
Citrafleet®

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Non Formulary

Oral powder.

 
Co-danthramer
(Dantron)

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Non Formulary

  • Capsules have been discontinued. Supplies of co-danthramer are unlikely to be available and co-danthramer strong expected to last until Dec 15.
  • Not generally recommended due to the risk of dantron burns and control is usually acheived with alternatives.
  • Suspension is very expensive.

 
Co-magaldrox  (Mucogel®)

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Non Formulary
 
Darvadstrocel  (Alofisel®)

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Non Formulary
Black

Not recommended for treating complex perianal fistulas in Crohn’s disease as per NICE TA556. 

APCO March 2019.

Link  NICE TA556: Darvadstrocel for treating complex perianal fistulas in Crohn’s disease
 
Dicycloverine

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Non Formulary
 
Dicycloverine  (Kolanticon®)

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Non Formulary
 
Docusate  (Norgalax® Micro-enema)

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Non Formulary

Micro-enema

 
Esomeprazole
(20mg tablet)

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Non Formulary
Black

Omeprazole and lansoprazole capsules are current first line choices.

Omeprazole 40mg is equivalent to esomeprazole 20mg in terms of bioavailability.

APCO March 2011.

 
Famotidine

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Non Formulary
 
Gastrocote

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Non Formulary

Product discontinued. 

 
Gripe Mixture

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Non Formulary

Available to purchase over the counter for infantile colic.

 
Haemorrhoid relief ointment

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Non Formulary

Various preparations available over the counter. 

 
Haemorrhoid relief suppositories

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Non Formulary

Various preparations available over the counter. 

 
Hydrotalcite

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Non Formulary
 
Izinova®

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Non Formulary

Bowel Preparation kit Containing sodium sulphate anhydrous, magnesium sulphate heptahydrate and potassium sulphate.

 
Kaolin and Morphine Mixture

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Non Formulary
 
Kaolin, Light

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Non Formulary
 
Lidocaine 5% ointment

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Non Formulary
 
Linaclotide  (Constella®)

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Non Formulary
Black

Not recommended for irritable bowel syndrome with constipation due to cost-effectiveness.

APCO November 2015.

 
Liquid Paraffin

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Non Formulary
 
Loperamide  (Imodium® Plus)

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Non Formulary

Available to purchase over the counter.

 
Lubiprostone  (Amitiza®)

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Non Formulary

This is now discontinued in the UK and NICE TA318 has been withdrawn. 

Link  NICE TA318: Lubiprostone for treating chronic idiopathic constipation
 
Maalox Plus

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Non Formulary
 
Macrogol  (Movicol liquid®)

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Non Formulary

Movicol is non-formulary. Please use Laxido instead as this is more cost-effective.

 
Macrogol oral powder
(Movicol®)

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Non Formulary

Movicol is Non-Formulary. Please use Laxido instead, which is the macrogol of choice at the OUH.

 
Magnesium Carbonate

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Non Formulary
 
Magnesium Trisilicate Mixture BP

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Non Formulary
 
Mebeverine with Ispaghula husk  (Fybogel® Mebeverine)

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Non Formulary
 
Mesalazine  (Ipocol®)

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Non Formulary
 
Mesalazine  (Mezavant® XL)

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Non Formulary
 
Methycellulose  (Celevac®)

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Non Formulary
 
Methylnaltrexone  (Relistor®)

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Non Formulary
Black

  • For opioid-induced bowel dysfunction in people with advanced illness receiving palliative care. NICE TA277 - terminated appraisal (APCO May 2013).
  • For treating opioid-induced constipation. NICE TA277 - terminated appraisal (APCO September 2017).

 
Micro-enema  (Relaxit®)

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Non Formulary

Use Micolette® or Micralax® 

 

 
Nizatidine

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Non Formulary
 
Omeprazole
(Gastro-resistant tablet)

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Non Formulary

Omeprazole capsules are first line choices.

 
Pancreatin  (Pancrease® HL)

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Non Formulary

Pancrease HL® and Nutrizym 22® should not be used in children aged 15 years or less with cystic fibrosis due to risk of the development of large bowel strictures (fibrosing colonopathy).

 
Pancreatin  (Pancrex®)

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Non Formulary
 
Pancreatin  (Pancrex® V)
(Tablets)

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Non Formulary

Tablets are non-formulary. Consider powder or capsules only

 
Pantoprazole

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Non Formulary

Omeprazole and lansoprazole capsules are current first line choices.

 
Peppermint Oil  (Mintec®)

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Non Formulary
 
Peppermint water

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Non Formulary
 
Perinal®

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Non Formulary
 
Phosphates (Oral)  (Diafalk®)

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Non Formulary
 
Phosphates (Oral)  (OsmoPrep®)

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Non Formulary
 
Prednisolone
(Enteric-coated tablet)

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Non Formulary
Black

Lack of evidence of cost-efficacy.

APCO January 2011.  

Link  UKMI Q&A: Q&A Is there any evidence to support the use of enteric coated (EC) over uncoated prednisolone tablets?
 
Prednisolone  (Predenema®)
(Rectal)

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Non Formulary
 
Probiotic  (Actimel®)

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Non Formulary
Black

Not recommended due to insufficient evidence of clinical and cost effectiveness in line with Clinical Commissioning Policy 125b.

Priorities Committee October 2008.

 
Proctosedyl®

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Non Formulary
 
Rabeprazole  (Pariet®)

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Non Formulary

Omeprazole and lansoprazole capsules are current first line choices.

 
Racecadotril  (Hidrasec®)

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Non Formulary
Black

Not recommended due to lack of evidence.

APCO March 2013.

 
Ranitidine Bismuth Citrate  (Pylorid®)

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Non Formulary
 
Renie Duo

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Non Formulary
 
Rowachol®

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Non Formulary

Rowachol® raises biliary cholesterol solubility. It is not considered to be an useful adjunct.

 
Senna  (Manevac®)

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Non Formulary
 
Senna  (Senokot®) (Granules)

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Non Formulary
 
Simeticone  (Dentinox®)

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Non Formulary

Available to purchase over the counter. It is licensed for infantile colic but evidence of benefit is uncertain.

 
Simeticone  (infacol®)

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Non Formulary

Available to purchase over the counter. It is licensed for infantile colic but evidence of benefit is uncertain.

 
Sodium citrate 0.3M

Non Formulary

Solution for acid aspiration

 
Sodium cromoglicate  (Nalcrom®)
(Food allergy)

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Non Formulary
 
Sodium hydrogen carbonate 0.5g/Sodium dihydrogen phosphate 0.68g  (Lecicarbon® C)

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Non Formulary
 
Sterculia  (Normacol®)

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Non Formulary
 
Sterculia  (Normacol® plus)

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Non Formulary
 
Teduglutide  (Revestive®)

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Non Formulary
High Cost Medicine
 
Topal  (Topal®)

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Non Formulary

Product discontinued.

 
Tripotassium Dicitratobismuthate  (De-Noltab®)

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Non Formulary

Discontinued by manufacturer in July 2015.

NB. Pepto bismol tablets (liquid is black-listed in drug tariff) may be an alternative.

 
Ultraproct®

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Non Formulary
 
Uniroid-HC®

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Red: Medicines which should only be prescribed in secondary care by a specialist.  

Amber Continuation

Amber Continuation: Medicines which should be initiated or recommended by a specialist for continuation in primary care. The specialist must notify the GP that the prescribing responsibility has been transferred.   

Amber Shared Care Protocol

Amber Shared Care Protocol: Medicines which are appropriate to be initiated and stabilised by a specialist, once stabilised the medicine may be appropriate for responsibility to be transferred from secondary to primary care with the agreement of a GP and a formal ‘shared care’ agreement. The shared care protocol must be approved by the Area Prescribing Committee Oxfordshire (APCO).   

Green

Green: Medicines which are suitable for initiation and ongoing prescribing within primary care.   

Brown

Brown: Medicines which should only be prescribed in restricted circumstances.  

Black

Black: Medicines which are not recommended for use because of lack of evidence of clinical effectiveness, cost effectiveness or safety.  

OCCG Green

not used  

netFormulary