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 Formulary Chapter 2: Cardiovascular system - Full Chapter
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02.05.05.02  Expand sub section  Angiotensin-II receptor antagonists
Candesartan
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First Choice
Green

Candesartan is the preferred Angiotensin II receptor antagonist for patients intolerant of ACE inhibitors due to cough.

For heart failure, see The Management of Heart Failure in Primary Care.

 
Losartan
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Second Choice
Green

For patients intolerant of ACE inhibitors due to cough.

 
   
Irbesartan
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Formulary
Green

For patients intolerant of ACE inhibitors due to cough.

 
   
Sacubitril valsartan▼ (Entresto®)
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Formulary
Amber Shared Care Protocol

For the treatment of symptomatic chronic heart failure with reduced ejection fraction in line with Shared Care Protocol.

APCO January 2017.

Report ALL suspected adverse reactions for black triangle drugs to Yellow Card Scheme.

 
Link  NICE TA388: Sacubitril valsartan for heart failure
Link  SMC advice (March 2016)
   
 ....
 Non Formulary Items
Azilsartan  (Edarbi®)

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Non Formulary
Black

No evidence to support place in therapy over other cost-effective alternatives.

APCO September 2012.

 
Cozaar- Comp®
(Losartan & hydrochlorothiazide)

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Non Formulary
 
Eprosartan  (Teveten®)

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Non Formulary
 
Olmesartan  (Sevikar®)

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Non Formulary
 
Telmisartan

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Non Formulary
 
Valsartan

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Non Formulary

Several suppliers are experiencing intermittent supply issues with valsartan products.

 
  
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Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
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Link to adult BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Red: Medicines which should only be prescribed in secondary care by a specialist.  

Amber Continuation

Amber Continuation: Medicines which should be initiated or recommended by a specialist for continuation in primary care. The specialist must notify the GP that the prescribing responsibility has been transferred.   

Amber Shared Care Protocol

Amber Shared Care Protocol: Medicines which are appropriate to be initiated and stabilised by a specialist, once stabilised the medicine may be appropriate for responsibility to be transferred from secondary to primary care with the agreement of a GP and a formal ‘shared care’ agreement. The shared care protocol must be approved by the Area Prescribing Committee Oxfordshire (APCO).   

Green

Green: Medicines which are suitable for initiation and ongoing prescribing within primary care.   

Brown

Brown: Medicines which should only be prescribed in restricted circumstances.  

Black

Black: Medicines which are not recommended for use because of lack of evidence of clinical effectiveness, cost effectiveness or safety.  

OCCG Green

not used  

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