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 Formulary Chapter 2: Cardiovascular system - Full Chapter
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02.08.01  Expand sub section  Parenteral anticoagulants
Argatroban (Exembol®)
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Formulary
Red

Secondary care use only. 

 
   
02.08.01  Expand sub section  Heparin
Heparin
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Formulary
Red

Secondary care use only. 

 
   
02.08.01  Expand sub section  Low molecular weight heparins
Dalteparin (Fragmin®)
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Formulary

In line with Dalteparin Guideline and Shared Care Protocol for Primary Care:

Amber Traffic Light  For sub-therapeutic INRs, DVT in patients with cancer, IV drug users & first doses in high risk of VTE in pregnancy.

Red Traffic Light  For perioperative anticoagulation, extended thromboprophylaxis & post-partum, trauma and intermediate risk of VTE in pregnancy.

Brown Traffic Light  For DVT & long haul flight prophylaxis.

APCO September 2016.

Brown Traffic Light For DVT (out of hours), in line with DVT service specification. Prescribe one off initial dose only if presentation of DVT outside of DVT clinic hours.

APCO September 2018.

Red Traffic Light For venous thromboprophylaxis for lower limb immobilisation. 

APCO July 2017.

NB. More information can be found on the OUHFT Anticoagulation & Thrombosis page.

 
   
Tinzaparin (Innohep®)
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Black Traffic Light  For Oxfordshire patients. Dalteparin is LMWH of choice in Oxfordshire.

APCO September 2008.

Amber Traffic Light For South East locality patients referred by Royal Berkshire Hospital Foundation Trust ONLY. In line with Royal Berkshire Hospital Foundation Trust Shared Care Protocol.

APCO January 2014.

 
   
02.08.01  Expand sub section  Heparinoids
Danaparoid (Orgaran®)
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Formulary
Red

Secondary care use only. 

 
   
02.08.01  Expand sub section  Hirudins to top
Bivalirudin (Angiox®)
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Red

For the treatment of ST-segment-elevation myocardial infarction as per NICE TA230.

 
Link  MHRA Drug Safety Update: Risks associated with incorrect dose
Link  NICE TA230 : Bivalirudin for the treatment of STEMI, 2011
   
02.08.01  Expand sub section  Heparin flushes
Heparin
(Flush)
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Formulary
Amber Continuation

Suitable for continuation in primary care following specialist initiation.

 
Link  UKMI Q&A: Heparin vs saline flushes for maintenance of patency in intravascular catheters & cannulae
   
02.08.01  Expand sub section  Epoprostenol
Epoprostenol (Flolan®)
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Formulary
Red
High Cost Medicine

Specialist prescribing only.

Funded by specialised commissioning.

 
Link  MHRA: Incompatibilities between Veletri and some administration devices
   
02.08.01  Expand sub section  Fondaparinux
Fondaparinux (Arixtra®)
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Formulary
Red

Secondary care use only. 

 
   
 ....
 Non Formulary Items
Enoxaparin  (Clexane®)

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Non Formulary
Black

Dalteparin is LMWH of choice in line with the OUHFT.

APCO September 2008.

 
Lepirudin

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Red: Medicines which should only be prescribed in secondary care by a specialist.  

Amber Continuation

Amber Continuation: Medicines which should be initiated or recommended by a specialist for continuation in primary care. The specialist must notify the GP that the prescribing responsibility has been transferred.   

Amber Shared Care Protocol

Amber Shared Care Protocol: Medicines which are appropriate to be initiated and stabilised by a specialist, once stabilised the medicine may be appropriate for responsibility to be transferred from secondary to primary care with the agreement of a GP and a formal ‘shared care’ agreement. The shared care protocol must be approved by the Area Prescribing Committee Oxfordshire (APCO).   

Green

Green: Medicines which are suitable for initiation and ongoing prescribing within primary care.   

Brown

Brown: Medicines which should only be prescribed in restricted circumstances.  

Black

Black: Medicines which are not recommended for use because of lack of evidence of clinical effectiveness, cost effectiveness or safety.  

OCCG Green

not used  

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