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 Formulary Chapter 5: Infections - Full Chapter
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05.02  Expand sub section  Antifungal drugs
Fluconazole
(Oral)
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Formulary
Green

In line with SCAN guidelines.

 
Link  UKMI Q&A: Can oral fluconazole be used with breastfeeding?
   
Griseofulvin
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Formulary
Green

In line with SCAN guidelines.

 
   
Terbinafine
(Oral)
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Restricted Drug Restricted
Brown

Prescribe in line with NICE CKS and SCAN guidelines.

Not licensed in children. 

APCO November 2018.

 
   
Itraconazole
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Restricted Drug Restricted
Brown

Prescribe in line with NICE CKS and SCAN guidelines.

 
   
Amphotericin (AmBisome®)
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Formulary
Red
High Cost Medicine

Secondary care use only. 

APCO July 2010.

 
   
Amphotericin (Fungizone®)
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Formulary
Red

Secondary care use only. 

APCO July 2010.

 
Link  NPSA alert on injectable amphotericin
   
Fluconazole
(Injection)
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Formulary
Red

Secondary care use only. 

APCO July 2010.

 
   
Flucytosine (Ancotil®)
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Formulary
Red

Secondary care use only. 

APCO July 2010.

 
   
Isavuconazole (Cresemba®)
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Formulary
Red

For treatment of fungal infections if resistance/intolerance to alternatives.

APCO March 2017.

 
   
Ketoconazole
(Oral)
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Formulary
Red

Secondary care use only. 

APCO July 2010.

 
   
Posaconazole (Noxafil®)
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Formulary
Red
High Cost Medicine

For the treatment of high risk invasive fungal infections.

APCO November 2006.

 
Link  Posaconazole tablet and oral suspension not interchangeable - HCP letter
   
Voriconazole (Vfend®)
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Formulary
Red
High Cost Medicine

Antifungal agent in haematology patients. Secondary care use only. 

APCO July 2003.

 
Link  MHRA: reminder of risk of liver toxicity, phototoxicity, and squamous cell carcinoma
   
05.02  Expand sub section  Treatment of fungal infections
05.02  Expand sub section  Drugs used in fungal infections
05.02.01  Expand sub section  Triazole antifungals
05.02.02  Expand sub section  Imidazole antifungals to top
05.02.03  Expand sub section  Polyene antifungals
05.02.04  Expand sub section  Echinocandin antifungals
Micafungin (Mycamine®)
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Formulary
Red
High Cost Medicine

Secondary care use only. 

 
   
05.02.05  Expand sub section  Other antifungals
 ....
 Non Formulary Items
Amphotericin  (Abelcet®)

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Non Formulary
High Cost Medicine
 
Amphotericin  (Amphocil®)

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Non Formulary
 
Anidulafungin  (Ecalta®)

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Non Formulary
Black
High Cost Medicine

APCO July 2010.

 
Caspofungin  (Cancidas®)

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Non Formulary
High Cost Medicine
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Red: Medicines which should only be prescribed in secondary care by a specialist.  

Amber Continuation

Amber Continuation: Medicines which should be initiated or recommended by a specialist for continuation in primary care. The specialist must notify the GP that the prescribing responsibility has been transferred.   

Amber Shared Care Protocol

Amber Shared Care Protocol: Medicines which are appropriate to be initiated and stabilised by a specialist, once stabilised the medicine may be appropriate for responsibility to be transferred from secondary to primary care with the agreement of a GP and a formal ‘shared care’ agreement. The shared care protocol must be approved by the Area Prescribing Committee Oxfordshire (APCO).   

Green

Green: Medicines which are suitable for initiation and ongoing prescribing within primary care.   

Brown

Brown: Medicines which should only be prescribed in restricted circumstances.  

Black

Black: Medicines which are not recommended for use because of lack of evidence of clinical effectiveness, cost effectiveness or safety.  

OCCG Green

not used  

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