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 Formulary Chapter 9: Nutrition and blood - Full Chapter
09.01.04  Expand sub section  Drugs used in autoimmune thrombocytopenic purpura
Anagrelide (Xagrid®)
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Restricted Drug Restricted
Red

For second line use either after hydroxycarbamide failure or as an adjunct in those few cases where patients cannot tolerate a full dose of hydroxycarbamide.

To be used by Haematology consultant only.

APCO November 2007.

 
   
Caplacizumab
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Red

Secondary care use only for acquired thrombotic thrombocytopenic purpura, via patient access scheme. Approved at MMTC.

APCO May 2019.

 
   
Eltrombopag (Revolade®)
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High Cost Medicine

Red Traffic Light  For treating chronic immune (idiopathic) thrombocytopenic purpura as per NICE TA293.

Prior approval required.

APCO September 2013. 

Black Traffic Light  Severe aplastic anaemia refractory to immunosuppressive therapy (NICE TA382 - terminated appraisal).

APCO March 2016.

 
Link  NICE TA293: Eltrombopag for treating chronic ITP
   
Romiplostim (Nplate®)
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Red
High Cost Medicine

Prior approval required.

For the treatment of chronic immune (idiopathic) thrombocytopenic purpura as per TA221. 

APCO May 2011.

 
Link  NICE TA221: Thrombocytopenic purpura - romiplostim
   
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Key
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Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
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Link to adult BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Red: Medicines which should only be prescribed in secondary care by a specialist.  

Amber Continuation

Amber Continuation: Medicines which should be initiated or recommended by a specialist for continuation in primary care. The specialist must notify the GP that the prescribing responsibility has been transferred.   

Amber Shared Care Protocol

Amber Shared Care Protocol: Medicines which are appropriate to be initiated and stabilised by a specialist, once stabilised the medicine may be appropriate for responsibility to be transferred from secondary to primary care with the agreement of a GP and a formal ‘shared care’ agreement. The shared care protocol must be approved by the Area Prescribing Committee Oxfordshire (APCO).   

Green

Green: Medicines which are suitable for initiation and ongoing prescribing within primary care.   

Brown

Brown: Medicines which should only be prescribed in restricted circumstances.  

Black

Black: Medicines which are not recommended for use because of lack of evidence of clinical effectiveness, cost effectiveness or safety.  

OCCG Green

not used  

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